Head of Sales - Sigmatic Sciences

About the Role

As Head of Sales, you own the sales motion for Sigmatic Sciences end-to-end — carrying the revenue number and building the team, methodology, and pipeline that deliver it. This is a global mandate weighted toward the United States and European markets, spanning new business, expansion, and retention across our Strategic Account Managers and Scientific Liaisons.

You will define how Sigmatic sells: the account planning, engagement model, and playbooks that make growth repeatable and forecastable. You will lead from the front — coaching the team while personally driving the most complex, highest-value deals. Marketing, Product, and Customer Success are your closest partners, and you will work in lockstep with them to convert demand, shape the roadmap, and secure long-term customer value. Sales execution, and the number, are yours.

This is a pivotal hire. You will build the growth engine that scales Sigmatic globally, turning a genuinely differentiated platform into commercial momentum in a market that is only beginning to grasp what lab-in-the-loop can do.

Working Location

This is a remote role based on the East Coast of the United States, with regular travel to meet your global team, key customers, and Sapio leadership.

Responsibilities

• Own the number. Carry and deliver Sigmatic's revenue targets across new business, expansion, and net revenue retention and take personal responsibility for the strategic accounts that anchor the annual plan.

• Define how Sigmatic sells. Establish the account-planning methodology, engagement cadences, and expansion playbooks that make growth predictable, with Scientific Liaisons deployed to lead business-value conversations at the core of the go-to-market model.

• Run a disciplined operating rhythm. Own forecasting, pipeline hygiene, CRM discipline, and a visible, relentlessly managed set of KPIs that underpin dependable performance.

• Own executive relationships. Serve as the senior point of partnership and escalation on your most important and most complex accounts.

• Partner with leadership. Work with the CCO and wider leadership to set targets, shape priorities, and report on the health of the sales portfolio.

• Collaborate across the go-to-market team. Work closely with Marketing, Product, and Customer Success — converting demand into pipeline, feeding customer and market intelligence into the roadmap, and aligning on retention and expansion — without owning those functions.

• Represent Sapio and Sigmatic. Show up with credibility at industry events, customer meetings, and executive briefings as a senior commercial leader.

Requirements

• A track record of leading enterprise B2B SaaS sales and consistently meeting or beating revenue, net revenue retention, and expansion targets in complex, multi-stakeholder accounts.

• Experience building and scaling a distributed sales or presales team across multiple geographies and cultures.

• Fluency in a recognized enterprise sales methodology (e.g., MEDDIC, Challenger, Force Management), with strong command of executive-level engagement and multi-year commercial negotiation.

• The ability to build the playbooks, cadences, and account plans a scaling team runs on — and to lead from the front on the hardest deals.

• Enough command of agentic AI, lab-in-the-loop, and in-silico approaches to sell their value credibly to scientific and executive buyers in therapy design and development.

• Experience selling into life sciences, biopharma, or diagnostics strongly preferred; familiarity with lab informatics and an existing network in pharma or biotech are distinct advantages.

Required Skills & Attributes

• Exceptional people leadership — you inspire, develop, and hold a distributed team accountable to a high bar.
• Strong executive presence and the credibility to engage C-suite and senior stakeholders as a peer.
• Commercial acumen across account planning, renewals, and expansion, with a data-driven approach to forecasting and performance.
• Clear, persuasive communication that builds trust quickly, both internally and with customers.
• A collaborative operator who influences without authority and thrives cross-functionally.
• Comfortable in a fast-paced scale-up where you build structure as you grow.
• Willing to travel regularly across the US and to Europe to support your team and key accounts.