Plume

Plume (operating at getplume.co) is a virtual gender-affirming care platform engineered for accessibility and equity in healthcare. Founded in 2019 and headquartered in Denver, Plume disrupts traditional barriers to transgender and gender-nonconforming care by offering comprehensive, trauma-informed services online. Unlike fragmented or location-dependent clinics, Plume consolidates one-on-one consultations, hormone replacement therapy (HRT), and mental health support through a network of licensed providers. Its model leverages telehealth infrastructure to deliver personalized care while addressing disparities in physical access, cost, and stigma. This allows transgender and nonbinary individuals to receive affirming treatment conveniently, without geographic or logistical constraints. Backed by $38M in funding—including a $24M round in August 2022—Plume aligns with top-tier venture capital backing while prioritizing community-driven solutions.