Senior Medical Science Liaison (Senior MSL) - Neurology/Epilepsy
Job Description
The Senior Medical Science Liaison (Senior MSL) role at Xenon Pharmaceuticals offers an opportunity to join a neuroscience-focused biopharmaceutical company dedicated to advancing life-changing therapeutics for patients with epilepsy, depression, and pain.
About the Role:
This field-facing position will engage with Healthcare Providers (HCPs), Key Opinion Leaders (KOLs), and patient groups to educate them about Xenon’s pipeline in epilepsy. The role covers the Southeast Region: Florida, Georgia, and Alabama, with a preference for candidates residing in Florida.
The ideal candidate is a clinical or scientific professional with a passion for science, deep scientific knowledge, and the ability to communicate complex medical information clearly. This role requires understanding the needs of HCPs, patients, and families while collaborating to solve critical scientific and business challenges.
Key Responsibilities:
- Identify, develop, and maintain valued relationships with KOLs, HCPs, academic institutions, payors, and advocacy groups.
- Act as a key scientific resource to communicate medical, clinical, and scientific information about Xenon’s neurology and epilepsy products and pipeline.
- Advance Xenon’s scientific platform and medical information in alignment with corporate objectives.
- Engage in projects aligned with medical strategies and adapt plans for the assigned territory.
- Identify and report scientific/clinical insights, trends, opportunities, and threats for targeted products.
- Collaborate with internal clinical development teams to enhance patient enrollment in clinical trials.
- Respond to and document unsolicited requests for scientific information.
- Lead national/regional congress activities in accordance with Medical Affairs strategies.
- Provide mentorship to new or less experienced MSLs.
- Travel domestically up to 50% of the time, including overnight travel, with potential ad-hoc international travel.
Qualifications:
- Minimum of a relevant doctorate degree (M.D., PhD, PharmD, DPH, DNP).
- Minimum 5 years of MSL-related experience, with 8+ years strongly preferred.
- Experience in the neurology therapeutic area or epilepsy required.
- Established relationships with KOLs and neurology institutions.
- Clinical trial development and drug launch experience strongly preferred.
- Effective communication skills to adjust messaging for diverse audiences.
- Proven ability to work independently and cross-functionally.
- Knowledge of clinical research processes, FDA regulations, and OIG guidelines required.
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Xenon Pharmaceuticals
View Company ProfileXenon Pharmaceuticals Inc. (operating under xenon-pharma.com) is the premier, enterprise-grade neuroscience biotechnology powerhouse, ion channel science pioneer, and therapeutic development innovation leader engineered to act as the definitive, high-velocity discovery and clinical-stage engine for transformative treatments across epilepsy, depression, and severe neurological conditions. Founded to bridge the gap between complex human genetic insights and the rigorous development of selective molecular chemistries, the company completely eliminates the severe systemic friction of modern CNS drug development—where traditional trial-and-error chemical synthesis fails to navigate the blood-brain barrier effectively, ignores critical genetic markers for patient stratification, and suffers from low signal-to-noise ratios in ion channel modulation—by deploying a sophisticated, biology-first computational and laboratory matrix. Moving far beyond traditional, passive small-molecule discovery pipelines, Xenon natively unifies deep, multi-decade proprietary human genetics databases, high-throughput ion channel assay screening platforms, and precision chemistry optimization frameworks into a single high-availability clinical development workspace. Its primary research engine centers on its potent, selective ion channel targeting capabilities, currently anchored by its late-stage investigational candidate, azetukalner, which serves as a flagship asset in the treatment of challenging neurological and psychiatric indications. Operating as a public-market titan (NASDAQ: XENE) with deep institutional backing, the corporation maintains a robust pipeline of high-potential neurological therapies while consistently pioneering advancements in peripheral and central nervous system signaling pathways. Under the hood, its technology core utilizes advanced predictive pharmacokinetic modeling, automated high-throughput electrophysiology, and rigorous clinical trial data orchestration designed to accelerate drug candidate translation from the bench to pivotal phase 3 study completion without losing structural regulatory compliance or scientific velocity. What sets Xenon apart is its uncompromising dedication to replacing fragile, historically stagnant neuroscience development models with absolute scientific predictability, genomic-driven patient stratification, and elite-tier clinical trial execution; by bridging the gap between performance-intensive structural biology and the immediate, critical needs of patients suffering from debilitating neurological conditions, the enterprise remains a definitive cornerstone of modern algorithmic biotechnology and global nervous system therapeutic transformation.
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