Scientific Contributor & Knowledge Leader in Applied Cellular Neuroscience
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Job Description
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Arvinas is a biotechnology company dedicated to improving patient lives through the discovery, development, and commercialization of therapies that degrade disease-causing proteins using its proprietary PROTAC Discovery Engine platform.
The role requires a hands-on, lab-focused scientist with expertise in driving neuroscience discovery programs via biochemical, immunocytochemical, and histochemical pharmacology readouts, with a strong preference for experience in high-content imaging (HCI) and histochemistry.
Principal Responsibilities
The incumbent will:
- Design and implement in vitro pharmacology readouts using cellular biochemical, functional, and image-based endpoints, including modalities like ELISA/MSD, quantitative Western Blot (WB), HCI, and bioluminescence-based assays.
- Provide technical and scientific leadership in immuno-histochemical endpoints for CNS and other tissues, contributing to a collaborative HCI working group focused on best practices and robust assay design solutions.
- Generate data to support program decision-making and communicate results to teams and senior leadership.
- Set and maintain high standards for data analysis and quality control (QC), driving innovative data interrogation methods.
- Interface with the automated biology organization to identify and drive automation-ready assay strategies.
Qualifications
The ideal candidate will:
- Have a demonstrated ability to balance speed with rigor in a fast-paced drug discovery environment.
- Possess systematic troubleshooting skills for biological assay systems.
- Be an energetic, positive leader with the capacity to grow into a team leader.
Must be legally authorized to work in the US without employer sponsorship.
Education
B.S. / M.S. with 12+ years of experience, or a Ph.D. with 2-5 years of experience in imaging, cellular and molecular biology, pharmacology, biochemistry, assay development, and biomolecular screening. A neuroscience background with pharma/biotech experience is preferred.
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Arvinas
View Company ProfileArvinas (operating at arvinas.com) is a clinical-stage biotechnology company pioneering **targeted protein degradation therapeutics**, a groundbreaking approach to treating debilitating and life-threatening diseases. Founded with a mission to redefine drug development, the company leverages proprietary technology to degrade disease-causing proteins directly within cells—a paradigm shift from traditional small-molecule or antibody-based therapies. By harnessing its platform, Arvinas enables precise modulation of pathological proteins linked to cancer, neurodegenerative disorders, and autoimmune diseases, offering potential cures where conventional treatments fall short. Patients and researchers benefit from a new class of drugs with enhanced specificity and reduced off-target effects. Backed by over **$462 million in funding** as of mid-2026, including a recent **$55 million Series C round led by Nextech Invest**, Arvinas is accelerating its lead oncology programs into clinical trials while expanding its early-stage pipeline.
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