Director Commercial FP&A

Location

This position may be performed remotely, but requires the flexibility and willingness to travel as needed.

The Opportunity

Praxis Medicines is seeking a Commercial FP&A leader to serve as a strategic finance partner to our Commercial organization as we prepare for launch and scale toward a multi-billion-dollar revenue organization. This role will support near-term launch readiness while also building the financial capabilities, discipline and insights required to operate at commercial scale over time.

This role sits within Finance but works in close, real-time partnership with Commercial, CMC and other cross-functional teams. The successful candidate will be deeply embedded in ongoing commercial workstreams, enabling forward-looking decision-making through continuous engagement rather than periodic reporting.

Primary Responsibilities

• Act as the primary FP&A partner to Commercial leadership, supporting brand strategy, launch planning and revenue forecasting from pre-launch through scale.
• Perform revenue modeling, scenario and sensitivity analyses and key commercial assumptions as the business grows to multi-billion-dollar revenue levels.
• Partner closely with CMC and Supply Chain teams on inventory assumptions, demand planning and working capital considerations.
• Collaborate cross-functionally on pricing, gross-to-net, market access and demand dynamics.
• Lead Commercial and CMC input into budgets, ongoing forecasts and long-range plans.
• Evaluate investment decisions through ROI analysis and financial modeling to support prioritization and resource allocation.
• Develop executive-ready materials that clearly communicate risks, opportunities and trade-offs.
• Continuously improves forecasting tools, processes and analytical rigor to support a scaling commercial organization.

Qualifications and Key Success Factors

• 12–15+ years of experience in FP&A or strategic finance, with strong commercial exposure
• Biopharma experience required, including experience supporting a commercial-stage company
• Experience supporting product launch and operating in a scaled commercial environment preferred
• Advanced financial modeling and analytical skills
• Proven ability to influence and partner with senior stakeholders across Finance, Commercial and CMC
• Strong business judgment and executive communication skills
• Comfortable operating in a fast-paced, evolving environment with ambiguity

Compensation & Benefits

At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive. This includes 99% of the premium paid for medical, dental and vision plans. We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future? We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP. We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns. Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring. We aim high, collaborate hard, and produce results. Let’s achieve the impossible together!

To round out our world-class total rewards package, we provide annualized base salary compensation in the range listed below. Final salary range may be modified commensurate with job level, education, and experience.